Sterility gene for mosquito controlScience News, December 18, 1971

Scientists are working hard to find a substitute for DDT in the control of malaria vector mosquitoes.… Two experiments with mosquitoes breeding in old tires in New Delhi point to an answer: a gene for sterility that would be passed to offspring.


Today, scientists are testing a variety of pesticide-free ways to control mosquito populations that spread malaria, Zika, dengue and yellow fever. One approach involves infecting male bloodsuckers with a strain of Wolbachia bacteria (SN: 6/10/17, p. 10). When the infected males mate with females, their offspring die before hatching. Another method tweaks mosquito DNA so that males pass on a daughter-killing trait and all female offspring die, shrinking populations over time. The mosquitoes, bred by the England-based biotech company Oxitec, took their first U.S. flight in May following a years-long debate about the safety of such organisms.

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